• Cammarata-Scalisi F, Natsuga K, Toyonaga E, Nishie W, Shimizu H, Stock F, Milano M, Petrosino P, Arenas de Sotolongo A, Medina Y:
    [Clinical and molecular findings of pachyonychia congenita type 2 (PC-2)].
    Gac Med Mex 151: 270-272, 2015.
  • Fujimura Y, Natsuga K, Abe R, Morita Y, Nomura T, Shimizu H:
    Plasma cell cheilitis extending beyond vermillion border.
    J Dermatol 42: 935-936, 2015.
  • Haga N, Abe R, Morita Y, Fujimura Y, Natsuga K, Nomura T, Kumakiri M, Shimizu H:
    Non-solar-induced elastotic bands on the forearm.
    Eur J Dermatol 25: 508-509, 2015.
  • Hata H, Abe R, Suto A, Homma E, Fujita Y, Aoyagi S, Shimizu H:
    MMP13 can be a useful differentiating marker between squamous cell carcinoma and benign hyperkeratotic lesions in recessive dystrophic epidermolysis bullosa.
    Br J Dermatol 172: 769-773, 2015.
  • Hata H, Aoyagi S, Homma E, Shimizu H:
    Lessons from 28 cases of reconstruction by lenticular island pedicle flap at a single institution.
    J Eur Acad Dermatol Venereol 29: 1015-1018, 2015.
  • Homma E, Hata H, Aoyagi S, Shimizu H:
    Primary mucinous carcinoma of the skin with in-transit metastasis.
    J Eur Acad Dermatol Venereol 29: 1655-1657, 2015.
  • Homma E, Hata H, Tsujiwaki M, Aoyagi S, Shimizu H:
    Nanoparticle albumin-bound paclitaxel can be useful agent to advanced primary mucinous carcinoma of the skin.
    J Eur Acad Dermatol Venereol 29: 2271-2273, 2015.
  • Horie K, Ito K, Hirata Y, Ito M:
    Eccrine poroma on the helix: a rare anatomical presentation.
    Clin Exp Dermatol 40: 442-444, 2015.
  • Horie K, Izumi K, Nishie W, Nomura T, Nomura Y, Arita K, Shimizu H:
    Deep venous thrombosis in patients with Behcet’s disease.
    J Dermatol 42: 101-102, 2015.
  • Hoshina D, Furuya K, Okita I:
    Erythema multiforme-like drug reaction with eosinophilia and systemic symptoms (DRESS).
    Clin Exp Dermatol 40: 455-456, 2015.
  • Iinuma S, Kishibe M, Saito N, Igawa S, Honma M, Takahashi H, Bando Y, Yoshida S, Iizuka H, Ishida-Yamamoto A:
    Klk8 is required for microabscess formation in a mouse imiquimod model of psoriasis.
    Exp Dermatol 24: 887-889, 2015.
  • Imafuku K, Hata H, Kitamura S, Iwata H, Shimizu H:
    In-transit metastasis of advanced eccrine porocarcinoma.
    International journal of dermatology 54: e503-505, 2015.
  • Imafuku K, Hata H, Kitamura S, Nomura T, Shimizu H:
    Diagnostic pitfall of localized lentigo accompanied by post-inflammatory pigmentation on the palm with a several-month history.
    Our Dermatol Online 6: 99-100, 2015.
  • Imafuku K, Nomura Y, Nakayama C, Abe R, Endo T, Shimizu H:
    Erythema annulare centrifugum-like mycosis fungoides after unrelated bone marrow transplantation.
    Br J Haematol 170: 140, 2015.
  • Ito T, Moriuchi R, Kikuchi K, Shimizu S:
    Pancreatic panniculitis.
    BMJ case reports, 2015.
  • Iwata H, Bieber K, Hirose M, Ludwig RJ:
    Animal models to investigate pathomechanisms and evaluate novel treatments for autoimmune bullous dermatoses.
    Curr Pharm Des 21: 2422-2439, 2015.
  • Iwata H, Pipi E, Mockel N, Sondermann P, Vorobyev A, van Beek N, Zillikens D, Ludwig RJ:
    Recombinant soluble CD32 suppresses disease progression in experimental epidermolysis bullosa acquisita.
    J Invest Dermatol 135: 916-919, 2015.
  • Iwata H, Witte M, Samavedam UK, Gupta Y, Shimizu A, Ishiko A, Schroder T, Seeger K, Dahlke M, Rades D, Zillikens D, Ludwig RJ:
    Radiosensitive Hematopoietic Cells Determine the Extent of Skin Inflammation in Experimental Epidermolysis Bullosa Acquisita.
    J Immunol 195: 1945-1954, 2015.
  • Kawakubo K, Hata H, Kawakami H, Kuwatani M, Kawahata S, Kubo K, Imafuku K, Kitamura S, Sakamoto N:
    Pazopanib-Induced Severe Acute Pancreatitis.
    Case Rep Oncol 8: 356-358, 2015.
  • Kitamura S, Hata H, Homma E, Aoyagi S, Shimizu H:
    Pigmented skin metastasis of breast cancer showing dermoscopic features of malignant melanoma.
    J Eur Acad Dermatol Venereol 29: 1034-1036, 2015.
  • Kitamura S, Hata H, Imafuku K, Haga N, Homma E, Shimizu H:
    Pazopanib can preserve cosmetic quality of life even in end-stage angiosarcoma.
    Clin Exp Dermatol 40: 931-933, 2015.
  • Kitamura S, Hata H, Inamura Y, Imafuku K, Sakashita T, Hirata K, Shimizu H:
    Positron emission tomography-computed tomography can be useful in the early detection of metastases in primary mucinous carcinoma of the skin on the head and neck.
    Br J Dermatol 173: 1263-1265, 2015.
  • Kitamura S, Hata H, Shimizu H:
    Dark-violaceous lesions on the dorsa of both hands.
    Clin Exp Dermatol 40: 941-942, 2015.
  • Kitamura S, Iwata H, Imafuku K, Hata H, Natsuga K, Aoyagi S, Shimizu H:
    Bowen’s disease on the palm presents refractory skin erosion without erythematous plaque.
    J Dermatol 42: 225-226, 2015.
  • Matsumura W, Ito K, Fujita Y, Watanabe E, Iitani MM, Nomura T, Sasaki M, Kobayashi H:
    Tuberculoid reaction to a cosmetic tattoo on the lips.
    Eur J Dermatol 25: 485-487, 2015.
  • Miyauchi T, Abe R, Morita Y, Adachi M, Shiba K, Hamade Y, Saito N, Nishimura M, Ibata M, Okada K, Shigematsu A, Endo T, Kawai K, Teshima T, Shimizu H:
    CD4/CD8 double-negative T-cell lymphoma: a variant of primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma?
    Acta Derm Venereol 95: 1024-1025, 2015.
  • Miyauchi T, Fujita Y, Takashima S, Morita Y, Suzuki S, Mizuno O, Saito N, Nomura T, Shimizu H:
    Pruritic Papules Following Lumbar Corset Use: A Quiz.
    Acta Derm Venereol 95: 762-765, 2015.
  • Miyauchi T, Nishie W, Sakata M, Osawa R, Noguchi A, Shimizu H:
    Sweet syndrome-like eruption with prominent dermal leukocytoclasis associated with systemic lupus erythematosus.
    J Dermatol 42: 442-443, 2015.
  • Mizuno O, Nomura T, Ohguchi Y, Suzuki S, Nomura Y, Hamade Y, Hoshina D, Sandilands A, Akiyama M, McLean WH, Abe R, Shimizu H:
    Loss-of-function mutations in the gene encoding filaggrin underlie a Japanese family with food-dependent exercise-induced anaphylaxis.
    J Eur Acad Dermatol Venereol 29: 805-808, 2015.
  • Moriuchi R, Ito T, Kikuchi K, Oshima Y, Shikano T, Takada H, Shimizu S:
    Elephantiasis nostras verrucosa occurring in voluntary shut-in (“hikikomori”).
    Eur J Dermatol 25: 76-77, 2015.
  • Moriuchi R, Nishie W, Ujiie H, Natsuga K, Shimizu H:
    In vivo analysis of IgE autoantibodies in bullous pemphigoid: A study of 100 cases.
    J Dermatol Sci 78: 21-25, 2015.
  • Nakayama C, Fujita Y, Watanabe M, Shimizu H:
    Development of bullous pemphigoid during treatment of psoriatic onycho-pachydermo periostitis with ustekinumab.
    J Dermatol 42: 996-998, 2015.
  • Nakayama C, Iwata H, Haga N, Hamade Y, Mizuno O, Nishie W, Shimizu H:
    The different intensity of autoantibody deposits in bullous pemphigoid associated with psoriasis vulgaris.
    Eur J Dermatol 25: 70-71, 2015.
  • Nakazato S, Fujita Y, Muramatsu K, Kikuchi K, Sato H, Shimizu H:
    A case of papular elastolytic giant cell granuloma: A mini-review of reported cases.
    Eur J Dermatol 25: 205-206, 2015.
  • Nishie W, Natsuga K, Iwata H, Izumi K, Ujiie H, Toyonaga E, Hata H, Nakamura H, Shimizu H:
    Context-Dependent Regulation of Collagen XVII Ectodomain Shedding in Skin.
    Am J Pathol 185: 1361-1371, 2015.
  • Nomura T, Mizuno O, Miyauchi T, Suzuki S, Shinkuma S, Hata H, Fujita Y, Akiyama M, Shimizu H:
    Striate palmoplantar keratoderma: Report of a novel DSG1 mutation and atypical clinical manifestations.
    J Dermatol Sci 80: 223-225, 2015.
  • Nomura T, Moriuchi R, Takeda M, Suzuki S, Kikuchi K, Ito T, Shimizu H, Shimizu S:
    Low-dose etretinate shows promise in management of punctate palmoplantar keratoderma type 1: Case report and review of the published work.
    J Dermatol 42: 889-892, 2015.
  • Nomura T, Yoneta A, Pohler E, Suzuki S, Osawa R, Mizuno O, Ohguchi Y, Nomura Y, Yamashita T, McLean WH, Shimizu H:
    Punctate Palmoplantar Keratoderma Type 1: A Novel AAGAB Mutation and Efficacy of Etretinate.
    Acta Derm Venereol 95: 110-111, 2015.
  • Prussmann W, Prussmann J, Koga H, Recke A, Iwata H, Juhl D, Gorg S, Henschler R, Hashimoto T, Schmidt E, Zillikens D, Ibrahim SM, Ludwig RJ:
    Prevalence of pemphigus and pemphigoid autoantibodies in the general population.
    Orphanet J Rare Dis 10: 63, 2015.
  • Sadeghi H, Lockmann A, Hund AC, Samavedam UK, Pipi E, Vafia K, Hauenschild E, Kalies K, Pas HH, Jonkman MF, Iwata H, Recke A, Schon MP, Zillikens D, Schmidt E, Ludwig RJ:
    Caspase-1-independent IL-1 release mediates blister formation in autoantibody-induced tissue injury through modulation of endothelial adhesion molecules.
    J Immunol 194: 3656-3663, 2015.
  • Sato H, Fujita Y, Hamade Y, Muramatsu K, Nakazato S, Kikuchi K, Haga N, Saito N, Shimizu H:
    Localized pemphigus vulgaris clinically masquerading as lichen planus and actinic keratosis.
    J Dermatol 42: 1204-1205, 2015.
  • Shiiya C, Hata H, Inamura Y, Imafuku K, Kitamura S, Fujita H, Shimizu H:
    Dermoscopic features of hidroacanthoma simplex: Usefulness in distinguishing it from Bowen’s disease and seborrheic keratosis.
    J Dermatol 42: 1002-1005, 2015.
  • Shimizu S, Inokuma D, Murata J, Kikuchi K, Ito T, Fukasawa Y, Mukai M, Moriuchi R:
    Cutaneous Manifestations of Methotrexate-associated Lymphoproliferative Disorders: Report of 2 Cases and a Review of the Literature.
    Acta Derm Venereol 95: 366-367, 2015.
  • Suda G, Yamamoto Y, Nagasaka A, Furuya K, Kudo M, Chuganji Y, Tsukuda Y, Tsunematsu S, Sato F, Terasita K, Nakai M, Horimoto H, Sho T, Natsuizaka M, Ogawa K, Ohnishi S, Chuma M, Fujita Y, Abe R, Taniguchi M, Nakagawa M, Asahina Y, Sakamoto N:
    Serum granulysin levels as a predictor of serious telaprevir-induced dermatological reactions.
    Hepatol Res 45: 837-845, 2015.
  • Suzuki S, Nomura T, Mizuno O, Fujita Y, Shimizu H:
    Identification of previously unknown SERPINB7 splice variants in patients with Nagashima-type palmoplantar keratosis reveals the importance of the CD-loop of SERPINB7.
    Br J Dermatol 173: 1288-1290, 2015.
  • Takashima S, Fujita Y, Miyauchi T, Nomura T, Nishie W, Hamaoka H, Shimizu H:
    Dermoscopic observation in adenoma of the nipple.
    J Dermatol 42: 341-342, 2015.
  • Takashima S, Iwata H, Sakata M, Osawa R, Nishie W, Shimizu H:
    Widespread erythema ab igne caused by hot bathing.
    J Eur Acad Dermatol Venereol 29: 2259-2261, 2015.
  • Takashima S, Okubo S, Ota M:
    An Iatrogenic Metastasis.
    Am J Med 128: e15-16, 2015.
  • Takashima S, Ota M:
    Creeping lymphangitis.
    BMJ 351: h5416, 2015.
  • Takashima S, Ota M:
    Methotrexate-induced nodulosis.
    CMAJ 187: E327, 2015.
  • Takashima S, Ota M:
    Herpes zoster triplex.
    Cleve Clin J Med 82: 579, 2015.
  • Toyonaga E, Hata H, Nakayama C, Homma E, Miyashita T, Shimizu H:
    A Rare Case of a Symptomatic Tumor Found in the Groin Area: An Atypical Location Unexposed to the Known Causes.
    Case Rep Oncol 8: 536-539, 2015.
  • Toyonaga E, Hata H, Shimizu H:
    Nipple-like tumour of the shoulder in a male patient.
    Clin Exp Dermatol 40: 700-702, 2015.
  • Toyonaga E, Nishie W, Komine M, Murata S, Shinkuma S, Natsuga K, Nakamura H, Ohtsuki M, Shimizu H:
    Skipped exon in COL7A1 determines the clinical phenotypes of dystrophic epidermolysis bullosa.
    Br J Dermatol 172: 1141-1144, 2015.
  • Tsujiwaki M, Hata H, Miyauchi T, Homma E, Aoyagi S, Shimizu H:
    Warty intralymphatic histiocytosis successfully treated with topical tacrolimus.
    J Eur Acad Dermatol Venereol 29: 2267-2269, 2015.
  • Vorobyev A, Ujiie H, Recke A, Buijsrogge JJ, Jonkman MF, Pas HH, Iwata H, Hashimoto T, Kim SC, Hoon Kim J, Groves R, Samavedam U, Gupta Y, Schmidt E, Zillikens D, Shimizu H, Ludwig RJ:
    Autoantibodies to Multiple Epitopes on the Non-Collagenous-1 Domain of Type VII Collagen Induce Blisters.
    J Invest Dermatol 135: 1565-1573, 2015.
  • Watanabe M, Ujiie H, Nishimura K, Kamiyama T, Abe R, Shimizu H:
    Mycosis fungoides associated with splenic infarction and muscle involvement.
    Br J Dermatol 173: 1100-1102, 2015.
  • Watanabe M, Ujiie H, Saito N, Abe R, Shimizu H:
    Kimura disease associated with severe visual dysfunction due to remarkable periorbital involvement.
    J Dermatol 42: 924-925, 2015.
  • Yanagi T, Matsuzawa S:
    PCTAIRE1/PCTK1/CDK16: a new oncotarget?
    Cell Cycle 14: 463-464, 2015.
  • Yanagi T, Shi R, Aza-Blanc P, Reed JC, Matsuzawa S:
    PCTAIRE1-Knockdown Sensitizes Cancer Cells to TNF Family Cytokines.
    PLoS One 10: e0119404, 2015.
  • Yang Z, Wilkie-Grantham RP, Yanagi T, Shu CW, Matsuzawa S, Reed JC:
    ATG4B (Autophagin-1) Phosphorylation Modulates Autophagy.
    J Biol Chem 290: 26549-26561, 2015.
  • 塩野谷愛香, 菊地一博, 平田悠, 中村裕之:
    臨床皮膚科 69: 560-564, 2015.
  • 吉川靖, 浜田亮, 西田剛士, 山本晃代, 富樫篤生, 山本大, 高橋浩師, 中村裕之, 足立憲昭:
    市立釧路医誌 27: 19-22, 2015.
  • 宮内俊成, 守内玲寧, 濱出洋平, 片岡浩, 近藤真, 山本聡, 向井正也, 清水聡子:
    市立札幌病院医誌 74: 271-277, 2015.
  • 月永一郎:
    KKR札幌医療センター医学雑誌 12: 121-122, 2015.
  • 月永一郎, 荒谷隆, 長谷川あゆこ, 加藤智子, 関根美香:
    KKR札幌医療センター医学雑誌 12: 51-55, 2015.
  • 月永一郎, 大島由季代, 竹内建人, 青山卓生:
    KKR札幌医療センター医学雑誌 12: 46-50, 2015.
  • 守内玲寧, 菊地一博, 伊東孝政, 伊東英里, 山口圭介, 清水聡子:
    臨床皮膚科 69: 595-598, 2015.
  • 中里信一, 村松憲, 北村真也, 佐藤英嗣:
    臨床皮膚科 69: 235-238, 2015.
  • 猪熊大輔, 月永一郎, 田村元, 三野和宏, 鈴木昭:
    Adenoma of the nippleの1例.
    皮膚科の臨床 57: 238-239, 2015.
  • 椎谷千尋, 夏賀健, 泉健太郎, 青柳哲, 清水宏:
    Piezogenic pedal papulesの3例.
    臨床皮膚科 69: 731-734, 2015.
  • 辻脇真澄, 保科大地, 古屋和彦:
    臨床皮膚科 69: 1027-1031, 2015.
  • 辻脇真澄, 保科大地, 古屋和彦, 石川耕資:
    皮膚科の臨床 57: 1097-1101, 2015.
  • 藤村悠, 辻康介, 佐藤英嗣:
    帯広厚生病院医誌 18: 64-66, 2015.
  • 平田悠, 羽賀直哉, 中村裕之:
    市立釧路医誌 27: 65-68, 2015.
  • 平田悠, 藤田靖幸, 大澤倫子, 西江渉, 清水宏:
    皮膚科の臨床 57: 2041-2044, 2015.
  • 對馬可菜, 秦洋郎, 稲村有香, 北村真也, 清水宏:
    皮膚科の臨床 57: 2092-2093, 2015.
  • 濱出洋平, 山本修司, 佐藤英嗣:
    マムシ咬傷の1例 -重症化の予測について-.
    臨床皮膚科 69: 427-430, 2015.


  • Natsuga K:
    Plectin-related skin diseases.
    J Dermatol Sci 77: 139-145, 2015.
  • Shinkuma S:
    Dystrophic epidermolysis bullosa: a review.
    Clin Cosmet Investig Dermatol 8: 275-284, 2015.
  • Ujiie H:
    IgE autoantibodies in bullous pemphigoid: Supporting role, or leading player?
    J Dermatol Sci 78: 5-10, 2015.
  • Yanagi T, Matsuzawa S:
    PCTAIRE1/PCTK1/CDK16: a new oncotarget?
    Cell Cycle 14: 463-464, 2015.
  • 阿部理一郎:
    Visual Dermatology 14: 1046-1049, 2015.
  • 夏賀健:
    別冊日本臨牀 新領域別症候群シリーズ 32: 168-172, 2015.
  • 氏家英之:
    Visual Dermatology 14: 1080-1083, 2015.
  • 清水宏, 夏賀健:
    臨床医学の展望14 皮膚科学.
    日本医事新報 4740: 74-77, 2015.
  • 西江渉:
    Visual Dermatology 14: 1076-1079, 2015.
  • 西村慶子, 阿部理一郎:
    急性発疹症対応マニュアル Stevens-Johnson 症候群/中毒性表皮壊死症の初期対応.
    MB Derma 232: 1-7, 2015.
  • 藤田靖幸:
    難病と在宅ケア 21: 29-33, 2015.
  • 藤田靖幸:
    MB Derma 236: 111-122, 2015.
  • 乃村俊史:
    Mebio 32: 10-15, 2015.
  • 乃村俊史:
    日本医事新報 4769: 64-65, 2015.
  • 本間英里奈:
    臨床皮膚科 69: 93-94, 2015.


  • Nishie W, Shimizu H: Doxycycline-Inducible Autoimmune Blistering Skin Disease Model. In: Nakao K, et al. (eds.): Innovative Medicine Basic Research and Development: Springer. 2015. pp 109-117.
  • 伊東孝政, 阿部理一郎: 薬疹検査法. 定番•外来皮膚科検査法のすべて. 東京: 文光堂. 2015. pp 49-52.
  • 伊東孝政, 夏賀健, 清水宏: 皮膚科的副作用とその対策. Bunkodo Essential & Advanced Mook 「ステロイド診療ガイド」. 東京: 文光堂. 2015. pp 213-215.
  • 西江渉: 表皮水疱症. 平成27年度日本皮膚科学会研修講習会テキスト(必須Aコース). 東京: 日本皮膚科学会. 2015. pp 1-7.
  • 西江渉: 水疱性類天疱瘡(含む妊娠性疱疹). 別冊日本臨牀 新領域別症候群シリーズ. 大阪: 日本臨牀社. 2015. pp 477-482.
  • 西江渉: 後天性表皮水疱症. 別冊日本臨牀 新領域別症候群シリーズ. 大阪: 日本臨牀社. 2015. pp 486-490.
  • 乃村俊史: 遺伝子検査. 定番•外来皮膚科検査法のすべて. 東京: 文光堂. 2015. pp 165-167.
  • 野村友希子, 清水宏: 皮膚とアンチエイジング. アンチエイジング医学の基礎と臨床. 東京: メジカルビュー社. 2015. pp 396-397.


  • 夏賀健:
    平成27年度長寿科学研究者支援事業. 2015.
  • 夏賀健:
    平成27年度総長室事業推進経費による研究支援事業(Fusion-H). 2015.
  • 夏賀健:
    日本研究皮膚科学会JSID’s Fellowship Shiseido Research Grant. 2015.
  • 夏賀健:
    第27回佐川がん研究助成. 2015.
  • 夏賀健:
    第26回コスメトロジー研究振興財団研究助成. 2015.
  • 夏賀健:
    2015年度GSKジャパン研究助成. 2015.
  • 今福恵輔:
    第114回日本皮膚科学会総会アブストラクト賞. 2015.
  • 氏家英之:
    第7回ロート皮膚医学研究賞. 2015.
  • 氏家英之:
    平成26年度冲中記念成人病研究所研究助成. 2015.
  • 氏家英之:
    2015度秋山財団研究助成(一般助成). 2015.
  • 氏家英之:
    武田科学振興財団 2015年度医学系研究奨励. 2015.
  • 松村若菜:
    第11回平成27年度 音羽博次奨学基金. 2015.
  • 新熊悟:
    加藤記念バイオサイエンス振興財団 第27回(平成27年度)国際交流助成. 2015.
  • 新熊悟:
    2015年度 秋山記念生命科学振興財団 研究助成(奨励). 2015.
  • 新熊悟:
    第30回(平成27年度)寿原記念財団研究助成. 2015.
  • 新熊悟:
    横山臨床薬理研究助成基金 平成27年度 研究助成. 2015.
  • 清水宏:
    2015年度秋山財団賞. 2015.
  • 清水宏:
    2015年度北海道医師会賞. 2015.
  • 清水宏:
    2015年度北海道知事賞. 2015.
  • 泉健太郎:
    JSIDきさらぎ応募賞. 2015.
  • 泉健太郎:
    平成27年度財団法人北海道大学クラーク記念財団 博士後期過程在学生研究助成. 2015.
  • 村松憲:
    日本皮膚科学会第400回北海道地方会ベストスライド賞. 2015.
  • 村松憲:
    平成26年度北海道地方会賞. 2015.
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    平成27年度財団法人北海道大学クラーク記念財団 博士後期過程在学生研究助成. 2015.
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    第11回平成27年度 音羽博次奨学基金. 2015.
  • 藤田靖幸:
    平成26年度(第27回)中冨健康科学振興財団 研究助成金. 2015.
  • 乃村俊史:
    平成27年度日本皮膚科学会基礎医学研究費(資生堂寄付). 2015.
  • 齋藤奈央:
    平成26年度北海道大学大学院医学研究科優秀論文賞. 2015.
  • 葭本倫大:日本皮膚科学会第401回北海道地方会ベストスライド賞. 2015.