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Chapter 22: Malignant Skin Tumors and Melanomas
Malignant skin tumors
A. Epidermal and follicular tumors

1. Basal cell carcinoma (BCC)
2. Squamous cell carcinoma (SCC)
3. Actinic keratosis
4. Bowen’s disease
5. Erythroplasia of Queyrat
6. Leukoplakia
7. Oral florid papillomatosis
8. Verrucous carcinoma
9. Keratoacanthoma

B. Sebaceous gland tumors

Sebaceous carcinoma

C. Sweat gland tumors

1. Mammary Paget’s disease
2. Extramammary Paget’s disease
3. Eccrine porocarcinoma
4. Microcystic adnexal carcinoma (MAC)
5. Mucinous carcinoma of the skin

D. Nervous system tumors

Merkel cell carcinoma

E. Mesenchymal tumors

a. Fibrous tissue tumors
1. Dermatofibrosarcoma protuberans (DFSP)
2. Malignant fibrous histiocytoma (MFH)
3. Atypical fibroxanthoma
4. Epithelioid sarcoma
5. Synovial sarcoma

b. Tumors of the fat cells

c. Vascular tumor
1. Angiosarcoma
2. Kaposi’s sarcoma

d. Histiocytic tumors
Langerhans cell histiocytosis (LCH)

e. Hematopoietic tumors
e-1. Cutaneous lymphoma
Cutaneous T-cell lymphomas
1. Mycosis fungoides (MF)
2. Sézary syndrome (SS)
3. Primary cutaneous anaplastic large-cell lymphoma
Supplement: Lymphomatoid papulosis
4. Pagetoid reticulosis (Woringer-Kolopp)
5. Adult T-cell leukemia/lymphoma (ATLL)
6. Natural killer (NK)/ T-cell lymphoma
7. Subcutaneous panniculitis-like T-cell lymphoma

Cutaneous B-cell lymphoma
1. Primary cutaneous marginal zone B-cell lymphoma
2. Primary cutaneous follicle center lymphoma
3. Primary cutaneous diffuse large B-cell lymphoma

e-2. Leukemia cutis
e-3. Multiple myeloma

F. Metastatic carcinoma of the skin

Metastatic carcinoma of the skin



Contents TOP
Author Profile
Structure and
Function of the Skin
Histopathology of the Skin
Immunology of the Skin
Skin Lesions
Diagnosis of Skin Diseases
Treatment of Skin Diseases
Eczema and Dermatitis
Urticaria, Prurigo and Pruritus
Erythema, Erythroderma
(Exfoliative Dermatitis)
Drug-Induced Skin Reactions
and GVHD
Vasculitis, Purpura and
Other Vascular Diseases
Collagen Diseases
Physiochemical Injury and
Photosensitive Diseases
Blistering and Pustular Diseases
Disorders of Abnormal Keratinization
Disorders of Skin Color
Metabolic Disorders
Disorders of the Dermis and Subcutaneous Fat
Disorders of the Skin Appendages
Nevus and Neurocutaneous Syndrome
Benign Skin Tumors
Malignant Skin Tumors and Melanomas
Viral Infections
Bacterial Infections
Fungal Diseases
Mycobacterial Infections
Sexually Transmitted
Skin Diseases Caused by Arthropods and Other Noxious Animals
Genodermatoses: Genetic Counseling and Prenatal Diagnosis
Dermoscopy: Appendix