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Recent 30 Departmental Original Publications ( 2005 - 2010 ) |
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1. Tanimura S, Tadokoro Y, Inomata K, Binh NT, Nishie W, Yamazaki S, Nakauchi H, Tanaka Y, McMillan JR, Sawamura D, Yancey K, Shimizu H, Nishimura EK:
Hair follicle stem cells provide a functional niche for melanocyte stem cells.
Cell Stem Cell 8: 177-187, 2011.(impact factor 25.943)
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2. Fujita Y, Abe R, Inokuma D, Sasaki M, Hoshina D, Natsuga K, Nishie W, McMillan JR, Nakamura H, Shimizu T, Akiyama M, Sawamura D, Shimizu H:
Bone marrow transplantation restores epidermal basement membrane protein expression and rescues epidermolysis bullosa model mice.
Proc Natl Acad Sci U S A 107: 14345-14350, 2010. (impact factor 9.432)
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2. Akiyama M, Sakai K, Yanagi T, Fukushima S, Ihn H, Hitomi K, Shimizu H:
Transglutaminase1 preferred substrate peptide K5 is an efficient tool in diagnosis of lamellar ichthyosis.
Am J Pathol 176: 1592-1599, 2010. (impact factor 5.673)
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3. Hamasaka A, Yoshioka N, Abe R, Kishino S, Umezawa K, Ozaki M, Todo S, Shimizu H:
Topical application of dehydroxymethylepoxyquinomicin improves allergic inflammation via NF-kappaB inhibition.
J Allergy Clin Immunol 126: 400-403, 2010. (impact factor 9.165)
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4. Natsuga K, Nishie W, Shinkuma S, Arita K, Nakamura H, Ohyama M, Osaka H, Kambara T, Hirako Y, Shimizu H:
Plectin deficiency leads to both muscular dystrophy and pyloric atresia in epidermolysis bullosa simplex.
Hum Mutat 31: E1687-1698, 2010. (impact factor 6.887)
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5. Natsuga K, Nishie W, Akiyama M, Nakamura H, Shinkuma S, McMillan JR, Nagasaki A, Has C, Ouchi T, Ishiko A, Hirako Y, Owaribe K, Sawamura D, Bruckner-Tuderman L, Shimizu H:
Plectin expression patterns determine two distinct subtypes of epidermolysis bullosa simplex.
Hum Mutat 31: 308-316, 2010. (impact factor 6.887)
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6. Nishie W, Lamer S, Schlosser A, Licarete E, Franzke CW, Hofmann SC, Jackow J, Sitaru C, Bruckner-Tuderman L:
Ectodomain shedding generates Neoepitopes on collagen XVII, the major autoantigen for bullous pemphigoid.
J Immunol 185: 4938-4947, 2010.
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7. Shinkuma S, Akiyama M, Inoue A, Aoki J, Natsuga K, Nomura T, Arita K, Abe R, Ito K, Nakamura H, Ujiie H, Shibaki A, Suga H, Tsunemi Y, Nishie W, Shimizu H:
Prevalent LIPH founder mutations lead to loss of P2Y5 activation ability of PA-PLA1alpha in autosomal recessive hypotrichosis.
Hum Mutat 31: 602-610, 2010.
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8. Wang G, Ujiie H, Shibaki A, Nishie W, Tateishi Y, Kikuchi K, Li Q, McMillan JR, Morioka H, Sawamura D, Nakamura H, Shimizu H:
Blockade of autoantibody-initiated tissue damage by using recombinant Fab antibody fragments against pathogenic autoantigen.
Am J Pathol 176: 914-925, 2010. |
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9. Yanagi T, Akiyama M, Nishihara H, Ishikawa J, Sakai K, Miyamura Y, Naoe A, Kitahara T, Tanaka S, Shimizu H:
Self-improvement of keratinocyte differentiation defects during skin maturation in ABCA12-deficient harlequin ichthyosis model mice.
Am J Pathol 177: 106-118, 2010.
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10. Ito K, Sawamura D, Goto M, Nakamura H, Nishie W, Sakai K, Natsuga K, Shinkuma S, Shibaki A, Uitto J, Denton CP, Nakajima O, Akiyama M, Shimizu H:
Keratinocyte-/fibroblast-targeted rescue of Col7a1 disrupted mice and generation of an exact dystrophic epidermolysis bullosa model using a human COL7A1 mutation.
Am J Pathol, 175: 2508-2517, 2009. (impact factor 5.697) |
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11. Nishie W, Sawamura D, Natsuga K, Shinkuma S, Goto M, Shibaki A, Ujiie H, Olasz E, Yancey KB, Shimizu H:
A novel humanized neonatal autoimmune blistering skin disease model induced by maternally transferred antibodies.
J Immunol 183: 4088-4093, 2009. (impact factor 6.000) |
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12. Inomata K, Aoto T, Binh NT, Okamoto N, Tanimura S, Wakayama T, Iseki S, Hara E, Masunaga T, Shimizu H, Nishimura EK:
Genotoxic stress abrogates renewal of melanocyte stem cells by triggering their differentiation.
Cell 137: 1088-1099, 2009.
(impact factor 31.253) |
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13. Hamasaka A, Abe R, Koyama Y, Yoshioka N, Fujita Y, Hoshina D, Sasaki M, Hirasawa T, Onodera S, Ohshima S, Leng L, Bucala R, Nishihira J, Shimizu T, Shimizu H:
DNA vaccination against macrophage migration inhibitory factor improves atopic dermatitis in murine models.
J Allergy Clin Immunol 124: 90-99, 2009.
(impact factor 9.773)
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14. Asaka T, Akiyama M, Domon T, Nishie W, Natsuga K, Fujita Y, Abe R, Kitagawa Y, Shimizu H:
Type XVII collagen is a key player in tooth enamel formation.
Am J Pathol 174: 91-100, 2009.
(impact factor 5.697) |
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15. Ando S, Abe R, Sasaki M, Murata J, Inokuma D, Shimizu H:
Bone marrow-derived cells are not the origin of the cancer stem cells in ultraviolet-induced skin cancer.
Am J Pathol 174: 595-601, 2009.
(impact factor 5.697) |
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16. Abe R, Yoshioka N, Murata J, Fujita Y, Shimizu H:
Granulysin as a marker for early diagnosis of the Stevens-Johnson syndrome.
Ann Intern Med 151: 514-515, 2009.
(impact factor 17.457) |
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17. Yanagi T, Akiyama M, Nishihara H, Sakai K, Nishie W, Tanaka S, Shimizu H:
Harlequin ichthyosis model mouse reveals alveolar collapse and severe fetal skin barrier defects.
Hum Mol Genet 17: 3075-3083, 2008.
(impact factor 7.249) |
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18. Sasaki M, Abe R, Fujita Y, Ando S, Inokuma D, Shimizu H:
Mesenchymal stem cells are recruited into wounded skin and contribute to wound repair by transdifferentiation into multiple skin cell type.
J Immunol 180: 2581-2587, 2008.
(impact factor 6.000) |
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19. Murata J, Abe R, Shimizu H:
Increased soluble Fas ligand levels in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis preceding skin detachment.
J Allergy Clin Immunol 122: 992-1000, 2008.
(impact factor 9.773) |
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20. Akiyama M, Sakai K, Takayama C, Yanagi T, Yamanaka Y, McMillan JR, Shimizu H:
CGI-58 is an alpha/beta-hydrolase within lipid transporting lamellar granules of differentiated keratinocytes.
Am J Pathol 173: 1349-1360, 2008.
(impact factor 5.697) |
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21. Nishie W, Sawamura D, Goto M, Ito K, Shibaki A, McMillan JR, Sakai K, Nakamura H, Olasz E, Yancey KB, Akiyama M, Shimizu H:
Humanization of autoantigen.
Nat Med 13:378-383, 2007. (impact factor 27.553) |
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22. Yamanaka Y, Akiyama M, Sugiyama-Nakagiri Y, Sakai K, Goto M, McMillan JR, Ota M, Sawamura D, Shimizu H.
Expression of the keratinocyte lipid transporter ABCA12 in developing and reconstituted human epidermis.
Am J Pathol 171: 43-52, 2007. (impact factor 5.697) |
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23. Nomura T, Sandilands A, Akiyama M, Liao H, Evans AT, Sakai K, Ota M, Sugiura H, Yamamoto K, Sato H, Palmer CN, Smith FJ, McLean WH, Shimizu H:
Unique mutations in the filaggrin gene in Japanese patients with ichthyosis vulgaris and atopic dermatitis.
J Allergy Clin Immunol 119:434-440, 2007. (impact factor 7.667) |
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24. Arita K, Akiyama M, Aizawa T, Umetsu Y, Segawa I, Goto M, Sawamura D, Demura M, Kawano K, Shimizu H:
A Novel N14Y Mutation in Connexin26 in Keratitis-Ichthyosis-Deafness Syndrome: Analyses of Altered Gap Junctional Communication and Molecular Structure of N Terminus of Mutated Connexin26.
Am J Pathol 169:416-423, 2006. (impact factor 5.697) |
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25. Fujita Y, Abe R, Sasaki M, Honda A, Furuichi M, Asano Y, Norisugi O, Shimizu T, Shimizu H:
Presence of circulating CCR10+ T cells and elevated serum CTACK/CCL27 in the early stage of mycosis fungoides.
Clin Cancer Res 12:2670-2675, 2006. (impact factor 6.488) |
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26. Sugiyama-Nakagiri Y, Akiyama M, Shibata S, Okano H, Shimizu H:
Expression of RNA-Binding Protein Musashi in Hair Follicle Development and Hair Cycle Progression.
Am J Pathol 168:80-92, 2006. (impact factor 5.697) |
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27. Inokuma D, Abe R, Fujita Y, Sasaki M, Shibaki A, Nakamura H, McMillan JR, Shimizu T, Shimizu H:
CTACK/CCL27 accelerates skin regeneration via accumulation of bone marrow derived-keratinocytes.
Stem Cells 24:2810-2816, 2006. (impact factor 7.741) |
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28. Akiyama M, Sugiyama-Nakagiri Y, Sakai K, McMillan JR, Goto M, Arita K, Tsuji-Abe Y, Tabata N, Matsuoka K, Sasaki R, Sawamura D, Shimizu H:
Mutations in lipid transporter ABCA12 in harlequin ichthyosis and functional recovery by corrective gene transfer.
J Clin Invest 115:1777-1784, 2005. (impact factor 16.559) |
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29. Yanagi T, Shimizu T, Abe R, Shimizu H:
Zinc dental fillings and palmoplantar pustulosis.
Lancet 366:1050, 2005. (impact factor 28.409) |
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30. Zhao Y, Shimizu T, Nishihira J, Koyama Y, Kushibiki T, Honda A, Watanabe H, Abe R, Tabata Y, Shimizu H:
Tissue regeneration using macrophage migration inhibitory factor-impregnated gelatin microbeads in cutaneous wounds.
Am J Pathol 167:1519-1529, 2005. (impact factor 5.697) |
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