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INTRODUCTION

Faculty
Professor & Chairman : Hiroshi Shimizu
Prof. Hiroshi Shimizu
Publication
M.D.,Keio University School of Medicine in 1979.
Ph.D., Keio University School of Medicine in 1985.

Research interests: Genetic diagnosis and gene therapy. Tissue engineering, Autoimmune diseases.Skin barrier and keratinization.

Since he opened the genetic counseling clinic for skin diseases, a range of patients have been referred to him from all over the world. He is also engaged in prenatal diagnosis and therapeutic research into several disorders. . Recent research includes the production of novel animal models for epidermolysis bullosa, bullous pemphigoid, and ichthyosis.As a leader of five large dermatology research groups, Hokkaido University has been developing several novel therapeutic strategies for blistering diseases and abnormal keratinization. Professor Shimizu has published more than 300 peer review English articles.

Senior associate Professor: Wataru Nishie
Publication
M.D., Hirosaki University in 1995.
Ph.D., Hokkaido University Graduate School of Medicine
in 2007.

Research interests: Autoimmune blistering skin diseases

Main project is generating novel therapeutic methods using several disease model mice.

Research interests: Inherited blistering skin diseases (Epidermolysis Bullosa)

Main project is generating novel therapeutic methods including gene, protein and cell therapies.

Associate Professor: Yasuyuki Fujita
Publication
M.D., Hokkaido University School of Medicine in 2002.
Ph.D., Hokkaido University Graduate School of Medicine
in 2010.

Research interest: Cell therapies for congenital skin disorders

Using disease-model mice, he investigates novel cell therapies for congenital sin disorders such as epidermolysis bullosa.

Assistant Professor: Hideyuki Ujiie
Yukiko Nomura
Publication
M.D., Hokkaido University in 2002.
Ph.D., Hokkaido University Graduate School of Medicine
in 2010.

Research interest: Autoimmune blistering skin diseases

He has been investigating the pathomechanisms of bullous pemphigoid and other autoimmune blistering diseases, especially from the viewpoint of immunology using disease model mice.

Assistant Professor: Toshifumi Nomura
Publication
M.D., Hokkaido University School of Medicine in 2002.
Ph.D., Hokkaido University Graduate School of Medicine
in 2009.

Research interest: Readthrough therapy

He has been developing small molecule drugs to rescue nonsense mutations in disease-causing genes in collaboration with Prof Irwin McLean at University of Dundee.

Research interest: 2. Atopic dermatitis and filaggrin gene mutation

He has carried out mutation analysis of the gene encoding filaggrin (FLG) in patients with atopic dermatitis (AD) and shown that FLG mutations predispose to AD in the Japanese population.

Assistant Professor: Hiroo Hata
Hiroo Hata
Publication
M.D., Hokkaido University School of Medicine in 2002.
Ph.D., Hokkaido University Graduate School of Medicine in 2013.

Research interest: Surgical education for residents

He always makes an effort to have residents acquire a surgical technique on the basis of participation of in practice.

Research interest: A study on the degree of malignancy of skin malignancy

He has studied a marker for invasion and proliferation and metastatic potential of skin cancer.

Assistant Professor: Ken Natsuga
Publication
M.D., Hokkaido University School of Medicine in 2003.
Ph.D., Hokkaido University Graduate School of Medicine
in 2010.

Research interest: Blistering skin diseases (epidermolysis bullosa, bullous pemphigoid),

He investigates novel therapies for inherited and autoimmune blistering skin diseases using disease-model mice.

Research interest: Regulation of skin microbiota by epidermal cells

He focuses on epithelial crosstalk at the microbiota-skin surface using molecular biological technique.

Assistant Professor: Hiroaki Iwata
Hiroaki Iwata
Publication
M.D., Gifu University in 1999.
Ph.D., Gifu University Graduate School of Medicine
in 2009.

Research interest: autoimmune blistering diseases

Research theme is to investigate the mechanisms of blister formation of bullous pemphigoid and epidermolysis bullosa acquisita.

Assistant Professor: Satoru Shinkuma
Yukiko Nomura
Publication
M.D., Nara Medical University in 2004.
Ph.D., Hokkaido University Graduate School of Medicine
in 2011.

Research interest: Gene therapy for epidermolysis bullosa

He has been investigating the safe gene therapies for the congenital blistering disease, epidermolysis bullosa.

Introduction
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Department Information
Message from the
Chairman
Faculty
Department Members
Recreation
Maps & Directions
Message from Prof. Shizmiu
Message from abroad
Message from Koshikai
Alumni Association Members
Ten years in retrospect

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